Researchers believe that this is the first time in thirty years and they have confirmed New antibiotics.
McMaster University in Ontario, Canada and University of Chiegago of the University of Illinois led by researcher Gerry Wright, collaborated to discover lariocidin, which was effective against drug-resistant bacteria.
The results were published this week in Nature magazine.
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Saloxidine is a lazoptide, a cannula-shaped bunch of amino acids that attack bacteria and prevent them from growing and surviving, McMaster’s press release said.
The researchers believe that this is the first time in three decades that they have identified a new antibiotic (not shown). (iStock)
It is Types of bacteria Called Paenibacillus, researchers retrieved local backyard soil samples and planted them in the lab for a year.
Paenibacillus was found to produce a new substance that attacks antibiotic-resistant bacteria.
“Lariocidine is not susceptible to many mechanisms Causes disease Researchers told Fox News Digital that it is resistant to bacteria with available antibiotics.
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The molecule has a unique structure of a “knotted lasso or pretzel”.
“Saloxidine binds to the molecular machine, ribosome, which binds all cellular proteins, which are one of the most important processes in cells,” the researchers said.
This finding is important given the increase in antimicrobial resistance, which the World Health Organization describes as a global public health threat. (iStock)
“It binds to specific sites in the ribosome, which does not have any known antibiotics in it and prevents the ribosome from producing proteins.”
Another key benefit of saloxidine is that it is not toxic to human cells, the researchers point out.
This finding is important given the increase in antimicrobial resistance, which the World Health Organization describes as global Public Health The threat accounts for 4.5 million people worldwide each year.
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“The antibiotic resistance crisis we are currently facing poses a significant threat to the way we do our medicine,” the researchers told Fox News Digital.
“If we continue to undergo unrestricted surgery, hip replacement, we need to prevent and treat infections Cancer Chemotherapytreatments for premature babies, etc. – So, we need new antibiotics to do this over the long term. ”
“The antibiotic resistance crisis we are currently facing poses a significant threat to the way we do our medicine.”
Dr. Marc Siegel, a medical clinical professor at NYU Langone Health and Fox News Health, appreciated the finding.
“AI Promising improvements in new drug targets including antibiotics – Meanwhile, Canadian McMaster’s research has discovered a new antibiotic. ” he told Fox News Digital.
Dr. Marc Siegel reiterated that no new antibiotics have appeared in decades – “partially because they are not so profitable because you only need them when you are sick.” (Istock/Fox News)
“This new antibiotic – lariocidin – works by interfering with the synthesis of proteins that many bacteria need to survive.”
Siegel reiterated that new antibiotics have not appeared for decades – “partially because they are not so profitable because you only need them when you are sick.”
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Stephen Vogel Weight management The findings say the choice is a “promising answer” to the infection caused by drug-resistant bacteria.
“Because this microorganism can kill bacteria in a way that cannot be developed, because its protein production system is called ribosomes, it has the potential to be a deadly diverse and enduring option. Bacterial infection,” North Carolina doctor told Fox News figures.
“The soil of the garden seems mundane, but in fact it is its own universe of microorganisms, fungi and bacteria, which may lead to key innovations, such as the promise brought by this discovery,” said one expert. (iStock)
According to Vogel, if this microorganism enters the market as an antibiotic, it means that the number of deaths from bacterial infections has decreased by millions each year.
He added: “Garden soil seems mundane, but in reality it is its own universe of microorganisms, fungi and bacteria, which could lead to key innovations such as the promise brought by this discovery.”
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Looking ahead, McMaster researchers will study the modification and production of newly discovered molecules for Clinical environmenta process that requires a lot of time and resources.
“This discovery is just the starting point for the long process of developing the molecule as a drug,” the researchers told Fox News Digital. (iStock)
“This discovery is just the starting point for the long process of developing the molecule as a drug,” the researchers told Fox News Digital.
“The next thing we’re going to do is test whether the saloxicide that can cure animals is effective in treating Multiple infections Among humans. ”
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Science is sometimes “accidental,” the researchers added.
“You usually have to shovel a lot of dirt before finding a gem, and lariocidin is of course. So, the money ‘dirty shovel’ is essential for finding new gems.”
