Experimental women's cancer drug boosts survival rates in notable study

A new drug shows hope in solving treatment options Ovarian cancer.

The drug clearing agent tested in the Phase 3 Rosella trial conducted by Corcept Therapeutics in California was found to improve overall survival and progression of the disease when matched with a chemotherapy drug called NAB-methfluoroformamide.

According to the press release, the Rosella trial, conducted in partnership with the GOG Foundation, analyzed 381 patients worldwide, including the United States, Europe, South Korea, Brazil, Argentina, Canada and Australia.

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Large, randomized phase 3 study showed that patients with platinum-resistant ovarian cancer had a 30% lower risk of disease progression compared to patients who had just received NAB-malonamide. (Some types of chemotherapy contain platinum.)

Female cancer patient sitting with female doctor at examination table

According to Corcept Therapeutics, patients with illness less than six months after receiving platinum therapy have “anti-platinum” disease. (iStock)

Researchers also point to “significant improvements” in overall survival Combination of drugs.

It is reported that the clearing agent is given as an oral pill and patients with increased side effects are “well tolerated”.

“There is a promising risk of recurrence by 30% and a 31% reduction in death risk.”

The drug was administered orally the day before, on the second day and one day after NAB-thyroxine therapy, and the drug was administered weekly by infusion.

The findings will be presented at a medical conference later this year, the researchers said. The results of the Phase 2 were published in the 2023 Journal of Clinical Oncology.

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Ovarian cancer is the fifth most common cause Cancer death in women According to the Ovarian Cancer Research Alliance, this is the deadliest of gynecological cancer.

Alexander B. Olawaiye, MD, Director of Gynecology Cancer Research Principal investigator at the Magee-Women Hospital and Rosella trial at the University of Pittsburgh, discussed the results with Fox News Digital.

It is reported that the clearing agent is given as an oral pill and patients with increased side effects are “well tolerated”. (iStock)

Olawaiye responded that the new agent was the “first kind” in the fight against cancers that don’t have many treatment options.

“That’s what makes the discovery of this study really exciting because it does survive without progress and Overall survival,” he said.

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Experts thanked his research team and mentioned that they “never stopped” as women Receive treatment.

“I want to congratulate women who are receiving treatment for ovarian cancer – first, helping us with this trial, second, we have the potential to have another option in the neighborhood now.”

The researchers said the patients in the trial showed a 30% decrease in the risk of death. (iStock)

Dr. Brian Slomovitz, director of the Cancer Research Council and chairman of the Cancer Research Council at Mount Sinai Medical Center in Miami Beach, Florida, commented on the findings in an interview with Fox News Digital.

“We know that ovarian cancer is very, very difficult, especially in patients with diseases that are resistant to standard chemotherapy,” he said.

“For a long time, we have been trying to find treatments that can help patients not only make the disease longer, but also Longer lifespan. Unfortunately, most trials are negative. ”

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Slomovitz, a member of the GOG Foundation, said he believes the Rosella trial is an “opportunity to use unique drugs” and shows “positive, encouraging outcomes.”

“The risk of recurrence is reduced by 30% and the risk of death is reduced by 31%,” he said.