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Prmagazine > News > News > Does Colossal Biosciences dire wolf creation justify its $10B+ valuation? | TechCrunch
Does Colossal Biosciences dire wolf creation justify its B+ valuation? | TechCrunch

Does Colossal Biosciences dire wolf creation justify its $10B+ valuation? | TechCrunch

On Monday, the giant bioscience of the “extinct” startup announced its most ambitious outcome to date: the terrifying wolf. These creatures have been extinct for over 12,000 years and are known for the HBO Show’s Game of Thrones.

These white fluffy animals live in a 2,000-acre reserve, in a so secretive location, journalists including Techcrunch were invited to watch the live animals and were not invited to the compound itself in the northern United States. Instead, we fly to another secret place and look at animals with our own eyes, because in this era of AI, a photo is unreliable.

There we saw two six-month-old men named Remus and Romulus, each weighing about 80 pounds. They looked at the inexperienced eyes, like big wild dogs, with a slightly larger skull and a lengthened muzzle. In addition to Remus and Romulus, the company’s scary wolf bags also include a two-month-old female Khaleesi.

Huge biologist scary wolf puppyImage source:Huge biological science

But the company said they had little to do with it. The giant wolf wolf is based on the result of an 18-month effort found in 13,000-year-old teeth and a fossil of an extinct animal skull with 72,000-year-old extinct animal.

When Huge Biological Sciences announces its latest fundraising Valuation of $10.2 billion Earlier this year, the company’s co-founder and CEO Ben Lamm told TechCrunch that he believes the startup is undervalued given its actual scientific advances.

Given the general initiation trend of overstating capabilities, it is not easy to make Lamm’s claim at face value, especially since Collosal’s ambitious wool mammoth and Tasmanian tiger’s ambitious de-extinction project is not completed until 2028.

Since then, the company has introduced a huge breakthrough that huge hopes will calm skeptics’ doubts about its scientific progress. Last month, the company announced that it would Mammoth’s fur. The wool mice caused a lot of excitement.

But it is clear that with the horror wolf, the company has taken its animal creation to the next level.

The company’s researchers compared ancient DNA with gray wolf and found that the species is genetically identical 99.5%. The scientists then used CRISPR technology to edit gray wolf cells with 20 genes that control the appearance of scary wolf. The transgenic cells become embryos, which are implanted into a large domestic dog, and then the terrifying wolf puppy is born.

The result is the first species to become extinct, the company claims.

Other scientists are skeptical

But whether many scientists who don’t work for huge questions represent a true species renaissance.

David Gold, a professor of paleontology at UC Davis, I suspect they behave differently from the real terrible wolf, too.”

Alexander Young, a professor of statistical genetics at UCLA, agrees. Written on X“This seems to be exaggerated.’Creating a terrible wolf requires only 20 edits of 20 genes in a regular gray wolf.” In other words, this is not a terrible wolf – it’s a gray wolf that looks more like a terrible wolf.

When asked about the gray wolf gene targeting altering the external manifestations of animals, a huge co-founder and professor of genetics at Harvard and MIT told TechCrunch if it was targeting TechCrunch, “Some of them are targeting the skull, which I think is internal.”

He added that only 0.3% of the gray wolf genes were altered to make horrible wolfs, and the remaining 0.2% of the mutations remained the same in the end.

Ben Lamm, Co-founder and CEO Colossal Biosciences Image source:Huge biological science

Lamm said Colossal did not use all the terrifying wolf genes because scientists fear that these genes will cause deafness and blindness. “From an ethical point of view, we feel we are not going to put that gene there.”

Now that we know Remus, Romulus and Khaleesi with animals roaming the world 100% until about 12,000 years ago, can we really call them devastating horror wolves?

According to gold, this is essentially a philosophical question. Another question is: Why should we be afraid of wolves?

Save the red wolf

Ram said the idea of ​​rebuilding the terrible wolf was enormous by “pure accidents.” “We have gained additional capital and are looking for other species that we can engage in.”

The Terrible Wolf represents the ideal blend of factors for a cash-rich startup, claiming to be morally conscious and with many Proficient in entertainment Investors are on their cap table.

“We love to stand out from conservation projects,” Lamm said.

A few years ago, the giant’s chief animal officers Lamm and Matt James learned from the North Carolina government that the red wolf is almost extinct and there are still less than 12 animals around the state. The country has been working hard to save them from disappearing. This discovery coincides with discussions with the North Dakota Native group about the sacredness of wolves in their culture. The company then brought George RR Martin, the author of the book “Game of Thrones” as a consultant to the company.

Huge bioscience red wolf
Huge bioscience red wolf Image source:Huge biological science

“It became a perfect Venn diagram. We can bring back a culturally relevant species that our indigenous partners care about, and we can use these technologies to save the red wolf.”

The giant wolf was also used to design giant technology to create four red wolf clones. The company plans to make more red wolves and eventually refocus them, which can save their species from extinction and increase biodiversity.

As for the horror wolf plan, Ram said the company could create about five more animals so they could live in a pack like wolves. Huge Huge also talks with the Indigenous community about the possibility of re-feeding horror wolves on their land. Currently, the company’s scientists and animal experts are spending time monitoring the behavior and health they create.

Is this really $10B+ business?

Then there is another problem: huge science shows that science is enough to attract investors to fund companies to upgrade their valuations. Time will tell, but there is reason to believe it can.

Lamm has arranged Several potential sources of income For the company. Colossal has divested two companies and plans to remove three more businesses over the next two years, one of which will be used for its artificial uterine technology, which could be applied for in fertility treatment.

The company may also start to collect help from the government for the protection of endangered animals one day. (Lamm says Colossal currently offers its protection technology for free.)

Finally, if the company successfully resurrects and reintroduces any species, reintroducing any species into its respective ecosystem, it may be able to generate revenue by selling biodiversity credit, a market-based mechanism similar to carbon credit.

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