Why microdosing Ozempic could become as common as taking a multivitamin

They may be in diabetes and lose weightbut GLP-1 drugs such as Ozempic and Wegovy are associated with expanding health benefits.

In fact, some doctors (including Dr. Terry Dubrow, a plastic surgeon based in Newport Beach, California, and TV celebrity) recommend everyone take a lower dose every day, even if they don’t need to lose weight.

Dubrow talked with Fox News Digital on the camera about the benefits of “micro-dose” of these drugs. (See the video at the top of this article.)

How GLP-1 works

GLP-1 receptor agonist Works by mimicking a hormone called glucagon peptide-1, which is released from the intestine after eating.

These drugs help regulate blood sugar, slow down stomach emptying and reduce appetite, and have been shown to reduce heart disease.

“Sugar is the enemy, and these drugs affect the sugar in your blood,” Dubro told Fox News figures. “They affect how insulin responds.”

Doctors say GLP-1 helps insulin to remove glucose (sugar) from the blood and into human cells, where it can be used for energy or storage. These drugs also help prevent inflammation and damage sugars caused in blood vessels, nerves and organs.

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“I don’t think anyone would argue that if there was a way to manipulate sugar levels and inflammation, that’s what we wanted to rely on. That’s exactly what these drugs do,” Dubro added.

In addition to regulating blood sugar and triggering lose weightGLP-1 has also been approved to reduce the risk of cardiovascular events and renal disease in some patients.

“I have never seen drugs in medical history be on such a rapid path to approval.”

“Even if you are not overweight, you can use these GLP-1 drugs … help minimize and prevent recurring heart attacks,” Dubro said.

Semaglutide has also recently been approved for use in MASH (metabolic dysfunction-associated steatohepatitis), an inflammatory form of fatty liver disease.

The potential of GLP-1 was also studied Cognitive Benefits In Parkinson’s patients.

“I’ve never seen a pathway to recognition in medical history such a rapid way of medicine,” Dubro said.

Micro-dose situation

Along with other experts, Dubrow is a advocate of microdose, which is when people take low doses of GLP-1 every day, even if they don’t need diabetes or obesity.

although Diabetic patients Take the dose that is increased every four weeks, and the micro dosage requires the use of a lower-level dose that does not increase.

Experts say

Dubrow noted that Tiktok’s young people zeroed in on microdoses – he thought everyone should do it.

“I’m fascinated by the concept of microdosing,” he said. “I think it’s probably half the starting dose of diabetes that is the way to go – you probably don’t need it every seven days, probably every 10 days, just adjusting the amount of sugar in the blood.”

Doctors point out that there are still many unknowns for GLP-1 drugs.

“We’re just figuring out how to use these drugs for different signs for different reasons,” he said. “We’re learning while we’re learning.”

“I am obsessed with the concept of microdosing.”

Like other drugs like Botox and other drugs, Dubrow says there are some “Human experiments“It’s playing.

“We’re figuring out that, we’re teaching the medical community how to do it. Patients tell us how to use these drugs.”

Potential risks

GLP-1 drugs have been associated with several potential risks. The most common one is Gastrointestinal problemssuch as nausea and vomiting.

Others reported an increased risk of pancreatitis, muscle loss and thyroid tumors.

“I read every study about these drugs and I can tell you that it’s obvious that they don’t cause the pancreas,” Dubro said.

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“In fact, if you really look at the people who are using it all the time, pancreatitis will be reduced in those populations.”

Dubrow confirmed that the drug is associated with very rare risks Medullary cancer thyroid.

“If you have family history Among them, this is the contraindication for you to use these drugs. ” he said.

Regarding the side effects of digestion, doctors say these drugs do slow down the gastrointestinal tract, but have shown that the body adapts to the medication over time.

“These special drugs are natural hormones that occur in our small intestine, and you’re used to the side effects. They’re gone.”

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Dubro pointed out that the severity of side effects is related to the dosage.

“Low doses, especially micro-doses, do have a low tendency to constipation, nausea, potential diarrhea, gerd (reflux),” he said. “I don’t think these side effects are very important for people with micro-sticks.”

To counteract the risk of muscle loss, Dubro recommends increasing protein intake and incorporating drug resistance training into a core component of exercise routine.

Those who experience severe side effects should Talk to the doctorhe suggested.

Pharmaceutical weight

When Fox News Digital contacts manufacturers of GLP-1 drugs, warns not to micron products.

“Eli Lilly has no data on the benefits or risks of Zepbough and Mounjaro microscopy,” said Eli Lilly, a spokesperson for GLP-1 Drugs Mounjaro and Zepbound. “Both auto-injectors and Zepbound vials are for single use only – the FDA label does not consider dose breakdown or microdose. Security risks. ”

“Not using Zepbough and Mounjaro can pose patient safety risks.”

Novo Nordisk, a manufacturer of Ozempic and Wegovy, said it does not tolerate “abuse” of its products.

“It is important to understand that for Wegovy, for Wegovy, obvious doses of only one-time fixed-dose pens (0.25, 0.5, 0.5, 1.0, 1.7 and 2.4 mg) are approved and represent the real FDA-approved medication,” a spokesperson told Fox News Digital. “The initial dose of Wegovy® is 0.25 mg per week and the dose will gradually increase. Patients should work with their doses. Professional medical staff Select 1.7 mg or 2.4 mg for maintenance dose. ”

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“It is also important to note that the real Wegovy injection pen is designed as a single-use pen, the dose has been set, should not be changed or tampered with, and the pen must be disposed of after one use.”

The spokesperson added: “The Ozempic is a multi-purpose pen with one pen and multiple needles.”

Visit GLP-1

Dubro said he was not worried about supply issues amid growing popularity of GLP-1, which is the main one Pharmaceutical companies There are resources to “scaling” to meet demand.

“It can be difficult for doctors who are willing to prescribe,” Dubrow said.

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Doctors warned against buying the drugs from online markets, which he called “Wild West”.

He warned: “It’s hard to find these drugs online from more complex pharmacies because they are rogues by nature – it’s illegal. They don’t allow it.”

“These drugs are natural hormones that occur in our small intestine and you get used to the side effects.”

“So if you get it from Rogue Pharmacies who don’t allow it or are willing to bend the rules, what is that? You don’t know what you’re getting.”

“This could be an adulterated, weird version with side effects, or it’s invalid.”

Looking to the future

How many are there Next Generation Drugs Dubro said that in the development of combining multiple hormone pathways.

He predicted: “I predict that within five years we will have a pill…in order to manipulate hunger and insulin resistance.”

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Overall, Dubro said the GLP-1 “stays here.”

“They just want to get better and we’re going to learn how to use them in a more appropriate and clinically effective way,” he said. “So fasten the seat belt. If you’re not here now, then you’ll be there later.”