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A common artificial sweetener can make Cancer treatment A new study found that it was less efficient.
According to research from the University of Pittsburgh and UPMC Hillman Cancer Center, sucralose is a sweetener found in many weight loss, a sweetener found in many weight loss, a low-calorie snack and powdered sugar alternative that may interfere with immunotherapy in cancer patients.
The study included 132 patients with melanoma (a fatal form) Skin cancer) and non-small cell lung cancer (the most common type of lung cancer).
Research finds that your daily soda may be much faster than you think
All patients used anti-PD1 (an immunotherapy) alone or in combination with chemotherapy.
They all filled out dietary questionnaires, indicating Artificial sweetener They consumed it.
Consumption of sucralose may interfere with immunotherapy in cancer patients. (iStock)
Researchers found that patients who consume high levels of cochlorate have “poor responses” to immunotherapy and “Poor survivalAccording to the press release, those who consume less than those who consume.
“We found that sucralose hinders the effectiveness of immunotherapy in various cancer types, stages and treatment modes,” said Diwakar Davar, an associate professor of medicine and medical oncologist and hematologist at the UPMC Hillman Cancer Center.
Sugar alternatives can cause brain changes and increase appetite, study says
“These observations increase the possibility of designing prebiotics, e.g. Supplement nutrition For patients who consume high levels of sucralose. ”
These findings are published in the Journal of the American Cancer Research Association for Cancer Discovery.
“It’s easy to say, ‘Stop eating soda’, but when patients are treated for cancer, they’re enough.”
From a positive point of view, the researchers also found that taking supplements increased levels of the amino acid arginine, counteracted these effects and enhanced them Effectiveness of immunotherapyas seen in a mouse study.
“It’s easy to say, ‘Stop drinking Diet Soda“However, when patients are treated for cancer, they are already dealing with enough things that it may not be realistic to ask them to change their diet significantly.”
Sucralose is a sweetener, low-calorie snack and powdered sugar alternative found in many weight loss. (iStock)
“We need to meet patients. That’s why it’s so exciting that arginine supplementation may be an easy way to counteract the negative effects of sucralose on immunotherapy.”
Sucralose was shown to change in mouse studies Intestinal microbiome To some extent, the arginine level is reduced. This amino acid is crucial for T cell function, a key component of immunotherapy drugs.
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“T cells fail to function properly when arginine levels are depleted due to changes in meclomalanose-driven in the microbiome,” OverAcre said. “So immunotherapy is not effective in mice fed with sucralose.”
“For people who are receiving cancer treatment, all guidance should come from their medical team.”
Looking ahead, researchers plan to launch Clinical trials Study arginine supplementation in human cancer patients. They will also explore the potential impact of other sugar alternatives on the effectiveness of immunotherapy.
The study was supported by the National Institutes of Health, the Damon Rooneyn Cancer Research Foundation and the Cancer Research Portal.
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The Calorie Control Commission provides the following statement to Fox News Digital.
“For people who are receiving cancer treatment, all guidance should come from their Medical Team,” said Council President Carla Saunders.
The researchers found that consuming high levels of co-methyl syrup responded to immunotherapy and “poor survival” worse than those consuming low amounts of patients. (iStock)
“This study has several limitations, relying on animal studies that cannot be applied directly to humans, and [is] A small observational study in humans using self-report Dietary datawhich is often affected by misunderstandings, inadequacy and prejudice. Despite the critical importance of ongoing research, global scientific regulators, including the FDA, have repeatedly confirmed the safety of methchlorite for decades. ”
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Fox News Digital contacted the manufacturer of sucralose-containing products for comment.
