Could GLP-1 weight-loss medications like Ozempic become the ‘everything drug’?

GLP-1 agonists, including Tirzepatides such as Ozempic and Wegovy, and Tirzepatides such as Mounjaro and Zepbough, were originally designed to treat type 2 diabetes and obesity.

But in recent months, studies have shown that these Popular drugs There are many other health benefits.

Some even claim that GLP-1 may eventually become the new “everything drug”.

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Dr. Angela Fitch, co-founder and chief medical officer of Nowwell, a Boston-based “weighted” healthcare company, said she would warn against labeling any drugs as “every drug,” but agreed that GLP-1S showed hope.

“GLP-1 is currently approved Treat obesityType 2 diabetes, secondary prevention of cardiovascular disease, metabolic-related fatty liver disease, chronic renal disease in patients with diabetes and sleep apnea. ”

“Further research is needed to determine its efficacy in the treatment of other chronic diseases.”

However, these drugs show “significant commitment” in areas such as addiction treatment and improvement of neurological diseases. Like Alzheimer’sFitch said.

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“They are lower blood pressureShe said lowers cholesterol and lowers visceral obesity. They also significantly improve the quality of life of patients. They have many clinical signs today, and many more. ”

The best benefits of GLP-1

Fitch lists the following major benefits of GLP-1 drugs.

• Promote effective fat loss and maintenance
• Control blood sugar and prevent patients at risk
• Lower blood pressure
• Improve lipids (to achieve healthy blood lipid type)
• Reduce the risk of heart and kidney disease

“These are not conveniences. They are the holy grail of modern medicine.”

Dr. Brett Osborn, a Florida neurosurgeon and longevity expert, believes that GLP-1 “stays here.”

“These drugs can not only treat obesity – from cardiovascular to neurodegenerative diseases, they have shown hope Addicted,” he told Fox News Numbers.

“I’ve said it before, and I’ll say it again: These are not conveniences. They are the holy grail of modern medicine.”

Potential risks and disadvantages

The most common side effects of GLP-1 drugs are Gastrointestinal tract related.

According to Fitch, these include nausea, vomiting, diarrhea, constipation and bloating, especially during the initial dose escalation.

“These symptoms “It usually improves over time, but it may limit some patients,” she said.

Experts warn that other more serious risks include pancreatitis, gallbladder disease and potential kidney damage – especially if severe dehydration occurs due to vomiting.

“Not everyone can tolerate them well, and we don’t have the full side effects yet.”

FOX News Senior Medical Analyst Dr. Marc Siegel has previously warned of the side effects of GLP-1S.

“Not everyone can tolerate them well, we don’t have the full side effects yet,” he told Fox News Digital at the time.

“I certainly think they are useful – many situations can be thought of, they reduce the risk heart diseasestroke, diabetes and cancer, and the need for bariatric surgery – but they certainly are not all of a certain degree – most are not first-line treatments. ”

Are all GLP-1s equal?

Not all GLP-1 receptor agonists are the same, Fitch warns.

“Although they all take the same basic pathway, their efficacy, side effect profiles and cardiovascular benefits can vary significantly,” she told Fox News Digital.

Semaglutide, such as Ozempic and Wegovy, is currently considered the most effective GLP-1s in both lose weight Fitch said there is evidence of cardiovascular benefits in patients with type 2 diabetes and obesity.

Banlupid was also just approved as MASH (metabolic dysfunction-related steatohepatitis, a severe fatty liver disease).

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“Tirzepatide (Mounjaro, Zepboughn) is a dual GIP/GLP-1 agonist that showed greater weight loss in trials with similar side effects in the trial,” Fitch said.

“Tirzepatide has been approved for sleep apnea and is undergoing clinical trials for other indications.”

Based on his own Clinical experienceOsborne reiterated that in many cases, Tilzaidet is a “superior agent”.

“It’s a biceps toxin, which means it targets two biochemical pathways,” he told Fox News Digital. “So, it’s no surprise for patients who stabilize on Wegovy, Zepbound, to start losing weight frequently.”

What to know before starting GLP-1

Fitch notes that GLP-1 is not a “magic bullet”, pointing to diet, exercise, sleep and Behavior change It is still crucial to reap the full benefits.

“Before taking GLP-1, people should also be aware that side effects are common and that consistent clinical care and supervision are required to ensure safety and efficacy,” she advises.

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“It’s not that people should only access through forms on the internet and access themselves without good, comprehensive, longitudinal care.”

For chronic diseases such as obesity or Type 2 diabetesFitch recommends long-term or even indefinitely as the best method.

“Once a healthy weight is achieved, dose reduction may become a viable maintenance strategy, although this approach is still under investigation,” she said.

“Patients should consult a doctor based on their specific needs to determine which action is the best.”

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Anyone interested in starting GLP-1 drugs should Consult a doctor Discuss potential benefits and risks.